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To what extent can early antiretroviral therapy play a role in the prevention of Human Immunodeficiency Virus infecton?

Vos, M (2012) To what extent can early antiretroviral therapy play a role in the prevention of Human Immunodeficiency Virus infecton? Bachelor's Thesis, Biology.

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Abstract

Treatment with combinations of different antiretroviral drugs, known as combined antiretroviral therapy, has declined morbidity and mortality due to AIDS. Antiretroviral drugs are also used as post-exposure prophylaxis and pre-exposure prophylaxis. Science declared the results of a study with compelling new evidence showing that antiretroviral drugs (ARVs) can prevent heterosexual HIV transmission as breakthrough of the year for 2011. Along with positive results of studies on antiretroviral therapy as pre-exposure prophylaxis of HIV infection, this study started enthusiasm for antiretroviral therapy as a tool for HIV prevention. High costs, non-adherence, drug resistance, drug toxicity and risk compensation are factors compromising the role of antiretroviral therapy in prevention. Although several studies have shown positive results, antiretroviral therapy is not the final solution in prevention of HIV infections. Priority of ART should remain for those with untreated advanced disease. However, when applied properly and in combination with the existing tools of prevention antiretroviral therapy can have a significant role in prevention of HIV infection worldwide.

Item Type: Thesis (Bachelor's Thesis)
Degree programme: Biology
Thesis type: Bachelor's Thesis
Language: English
Date Deposited: 15 Feb 2018 07:48
Last Modified: 15 Feb 2018 07:48
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/10187

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