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Riboswitch control: the regulatory function of prokaryotic RNAs

Viel, J. H. (2014) Riboswitch control: the regulatory function of prokaryotic RNAs. Bachelor's Thesis, Biology.

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Abstract

The expression of certain genes is regulated by riboswitches. These are RNA sequences situated prior to the ribosome binding site in messenger RNA. When binding a specific ligand, the riboswitch undergoes a conformation change which influences gene expression by inhibiting or stimulating transcription or translation. In this paper, the mechanisms of action employed by riboswitches, and the applicability of riboswitches in biotechnology, medicine and understanding evolutionary history is explored. It was concluded that riboswitches have high potential when it comes to biotechnology, might be useful for the development of new antibiotics, and while not overwhelming, add to the case of the RNA world hypothesis.

Item Type: Thesis (Bachelor's Thesis)
Degree programme: Biology
Thesis type: Bachelor's Thesis
Language: English
Date Deposited: 15 Feb 2018 07:57
Last Modified: 15 Feb 2018 07:57
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/11748

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