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Essay: The prokaryotic viral defense system CRISPR/Cas – a source for applications in research and biotechnology

Schmidt, I. L. (2014) Essay: The prokaryotic viral defense system CRISPR/Cas – a source for applications in research and biotechnology. Master's Thesis / Essay, Biology.

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Abstract

There are several systems established to defend prokaryotic cells against invaders. Only recently an adaptive immune system against invading nucleic acids, such as viruses or conjugative plasmids, was discovered. This system is called CRISPR/Cas (Clustered regularly interspaced short palindromic repeats/CRISPR associated (proteins)). Although it was since then extensively genetically and biochemically studied, there are still many processes that we do not fully understand and the diversity of CRISPR/Cas makes research even more challenging. However in this short time many practical applications for the CRISPR/Cas system, or certain parts of it, have emerged. Some of them are going to be used in research and some in biotechnology. Some of these applications are already in use and some of them are only conceivable. An important question is if these techniques are going to be seminal and what advantages these methods have over these that were in use before (in case there were any) and what alternatives there are and how long these methods are going to be in use before another method is going to replace a CRISPR/Cas based method.

Item Type: Thesis (Master's Thesis / Essay)
Degree programme: Biology
Thesis type: Master's Thesis / Essay
Language: English
Date Deposited: 15 Feb 2018 07:57
Last Modified: 15 Feb 2018 07:57
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/11875

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