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Through the Junction or Through the Body: the Choise of Neutrophils

Elhorst, P. (2014) Through the Junction or Through the Body: the Choise of Neutrophils. Bachelor's Thesis, Biology.

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Abstract

The ability of immune cells, including neutrophils, to exit the bloodstream is essential to immune system functioning. Trans-endothelial migration is a process whereby neutrophils exit the bloodstream by crossing the layer of endothelial cells lining the blood vessel in order to respond to infections. There are two possible ways in which neutrophils can migrate through the wall of blood vessels, either going through the junction of bordering endothelial cells, the well accepted paracellular pathway, or right through the body of an endothelial cell, the transcellular pathway. This thesis will show that transcellular trans-endothelial migration does exist, it will discuss the mechanisms implicated in these processes are and how the decision to use which of the two modes is made.

Item Type: Thesis (Bachelor's Thesis)
Degree programme: Biology
Thesis type: Bachelor's Thesis
Language: English
Date Deposited: 15 Feb 2018 07:57
Last Modified: 15 Feb 2018 07:57
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/11926

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