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Interkingdom Signalling Between Bacterial and Mammalian Cells

Devlitsarov, D. (2016) Interkingdom Signalling Between Bacterial and Mammalian Cells. Research Project 2 (major thesis), Molecular Biology and Biotechnology.

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Abstract

From the moment we are born, we are bombarded by the countless microorganism in our environment. Eukaryotes and prokaryotes have evolved side by side for billions of years, thus it is not surprising that they are able to detect and respond to each other’s chemical signals. By intercepting and reacting to each other’s signaling molecules, organisms engage in a finely tuned interplay which has far reaching impacts on their biology. But what kinds of chemical signals is interkingdom communication based on, and how do prokaryotes and eukaryotes recognize and respond to each other’s signals? In this report, we will explore the influence of bacterial signaling compounds on a eukaryotic host’s cognition and behavior, and examine the effects of eukaryotic hormones on microbiota. Additionally, we will talk about potential applications for microbiome engineering and discuss the implications behind interkingdom signaling and the Microbiota-Gut-Brain axis.

Item Type: Thesis (Research Project 2 (major thesis))
Degree programme: Molecular Biology and Biotechnology
Thesis type: Research Project 2 (major thesis)
Language: English
Date Deposited: 15 Feb 2018 08:11
Last Modified: 15 Feb 2018 08:11
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/13712

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