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The role of the endocannabinoid system in object recognition memory impairments by glucocorticoids and emotional arousal

Boer, J.W. de (2016) The role of the endocannabinoid system in object recognition memory impairments by glucocorticoids and emotional arousal. Research Project 2 (major thesis), Biomedical Sciences.

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Abstract

This study focuses on object recognition memory and object location memory. The first research question is: does an increase of corticosterone in rats impair retrieval of object recognition and location memory? A second research question addresses whether blockade of the CB1 receptor reverses such an impairment. SR141716, also known as Rimonabant, is an inverse agonist for the CB1 receptor and used to block eCB signaling in this study. The results show a decisive role for the endocannabinoid system.

Item Type: Thesis (Research Project 2 (major thesis))
Degree programme: Biomedical Sciences
Thesis type: Research Project 2 (major thesis)
Language: English
Date Deposited: 15 Feb 2018 08:25
Last Modified: 15 Feb 2018 08:25
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/14709

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