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The possibilities of organoid research in neurodegenerative diseases

Peletier, M. (2017) The possibilities of organoid research in neurodegenerative diseases. Bachelor's Thesis, Biology.

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Abstract

Neurodegenerative diseases are characterized by progressive neuronal loss in the central nervous system and peripheral nervous system but have been hard to study due to the inaccessibility of the brain in vivo. However, new in vitro models of the developing brain such as the new 3 dimensional brain organoids offer an unprecedented opportunity to study aspects of human brain development and disease. This relatively new technology has been used to investigate the neurological condition microcephaly as well as some neuropsychiatric disorders as autism and schizophrenia but has barely been studied in neurodegenerative diseases. This thesis demonstrates that combining different organoid- techniques could generate new possibilities and potential future models for organoid research in neurodegenerative diseases such as Alzheimer disease (AD) and Parkinson disease (PD).

Item Type: Thesis (Bachelor's Thesis)
Degree programme: Biology
Thesis type: Bachelor's Thesis
Language: English
Date Deposited: 15 Feb 2018 08:28
Last Modified: 15 Feb 2018 08:28
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/15163

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