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The role of the Blood Brain Barrier in the development and treatment of Alzheimer’s Disease

Peereboom, Anouk (2019) The role of the Blood Brain Barrier in the development and treatment of Alzheimer’s Disease. Bachelor's Thesis, Life Science and Technology.

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Abstract

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with an unknown etiology that accounts for 60 - 70% of all dementia cases (Burns and Iliffe, 2009; World Health Organization, 2016). The disease was first described by Alois Alzheimer in 1906 by examining a woman aged between 51 and 55 (Alzheimer, 1906). The blood brain barrier (BBB), which is the barrier between neuronal tissue and blood capillary cells, is suggested to be related in a certain way to AD pathogenesis and development (Yamazaki and Kanekiyo, 2017). The aim of this current study is to specify in which ways BBB’s functioning is related to AD pathogenesis and what this means for future therapeutic approaches in the treatment of AD.

Item Type: Thesis (Bachelor's Thesis)
Supervisor:
Supervisor nameSupervisor E mail
Eisel, U.L.M.U.L.M.Eisel@rug.nl
Degree programme: Life Science and Technology
Thesis type: Bachelor's Thesis
Language: English
Date Deposited: 12 Mar 2019
Last Modified: 13 Mar 2019 08:52
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/19256

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