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Influence of adenosine receptors in the striatum during sleep deprivation on declarative memory consolidation

Huisman, Stan (2019) Influence of adenosine receptors in the striatum during sleep deprivation on declarative memory consolidation. Bachelor's Thesis, Biology.

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Abstract

Sleep is one of the most important aspects of life. Nearly in a third of our life, we spend asleep. Research tries to figure out the purposes of sleep, like in memory consolidation. The hippocampus is one of the important brain structures for memory consolidation. During sleep deprivation, this process is disrupted in the hippocampus. Like the hippocampus, the striatum is also involved in memory consolidation. Both brain structures are closely linked, so the focus of this thesis was on striatal adenosine receptors and their influence on memory consolidation. The reviewed studies showed that A1R prevents memory consolidation due to inhibition of AC. A2AR stimulate AC and cause trouble in memory retrieval, but it is not certain if they obstruct memory processing and encoding. More investigation to proteins involved in memory processing and encoding is needed to reveal more about A2AR and memory.

Item Type: Thesis (Bachelor's Thesis)
Supervisor:
Supervisor nameSupervisor E mail
Havekes, R.R.Havekes@rug.nl
Degree programme: Biology
Thesis type: Bachelor's Thesis
Language: English
Date Deposited: 07 May 2019
Last Modified: 08 May 2019 09:37
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/19437

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