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1-Deoxy-D-xylulose-5-phosphate synthase: a promising target for novel antibiotics and antimalarials

Mulder, Fabian (2019) 1-Deoxy-D-xylulose-5-phosphate synthase: a promising target for novel antibiotics and antimalarials. Bachelor's Thesis, Pharmacy.

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Abstract

The enzyme 1-deoxy-D-xylulose 5-phosphate synthase (DXS) catalyses the formation of 1-deoxy-Dxylulose 5-phosphate (DXP) through the formation of a ternary complex consisting of DXS, Dglyceraldehyde 3-phosphate and a complex of pyruvate and thiamine diphosphate. This formation of DXP is the initial step in the methylerythritol phosphate (MEP) pathway.

Item Type: Thesis (Bachelor's Thesis)
Supervisor:
Supervisor nameSupervisor E mail
Groves, M.R.M.R.Groves@rug.nl
Degree programme: Pharmacy
Thesis type: Bachelor's Thesis
Language: English
Date Deposited: 04 Jun 2019
Last Modified: 13 Jun 2019 11:04
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/19579

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