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The Role of Lipid Droplets in Autophagy

Karnebeek, Benjan (2019) The Role of Lipid Droplets in Autophagy. Bachelor's Thesis, Biology.

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Abstract

Autophagy is a process in which proteins and organelles are engulfed in vesicles and then degraded by lysosomes or vacuoles. Autophagy is a process important in cellular homeostasis and its malfunction has been tied to several diseases. Lipid Droplets (LDs) are organelles that function as storage of neutral lipids and play a central role in cellular lipid metabolism. This review will outline the connections between LDs and (macro)autophagy and the involvement of LDs in autophagy. First an overview will be given of all proteins (discovered so far to be) involved in both lipid metabolism and (macro)autophagy and their functions in both. The consequences will then be discussed. Finally more direct functions of LDs in autophagy will be shown and the implications of these functions discussed.

Item Type: Thesis (Bachelor's Thesis)
Supervisor:
Supervisor nameSupervisor E mail
Klei, I.J. van derI.J.van.der.Klei@rug.nl
Degree programme: Biology
Thesis type: Bachelor's Thesis
Language: English
Date Deposited: 21 Jun 2019
Last Modified: 21 Jun 2019 12:47
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/19670

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