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The influences of genes and early life stress on the HPA axis regulation

Wuergezhen, Duligengaowa (2019) The influences of genes and early life stress on the HPA axis regulation. Master's Thesis / Essay, Biomedical Sciences.

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Abstract

Stress is considered as an uncontrollable and/or unpredictable cognitive perception expressed in physiological and behavioral responses, causing adverse emotional reactions and life events if not handled appropriately. HPA axis as a key regulator for adaptation to social and physical stressors, which is more sensitive to the adverse effects of life events during early childhood and adolescence periods. This may result in alterations in adult behavior and physiology as well as in individual differences in response to later stress exposure. The enduring effects of early life stress on gene expression may cause impaired HPA axis functioning, resulting in behavior and physiological alternation. This thesis will focus on the effects of early life stress on HPA axis regulation and genes which mediate the effects of ELS on risk for physiological disorder development by regulating or interfering with the HPA axis.

Item Type: Thesis (Master's Thesis / Essay)
Supervisor:
Supervisor nameSupervisor E mail
Buwalda, B.B.Buwalda@rug.nl
Degree programme: Biomedical Sciences
Thesis type: Master's Thesis / Essay
Language: English
Date Deposited: 12 Aug 2019
Last Modified: 13 Aug 2019 08:34
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/20645

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