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Complications remaining in the engineering of Saccharomyces cerevisiae towards the efficient hexose- and pentose-fermentation of lignocellulosic biomass

van den Beukel, Margot (2019) Complications remaining in the engineering of Saccharomyces cerevisiae towards the efficient hexose- and pentose-fermentation of lignocellulosic biomass. Bachelor's Thesis, Biology.

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Abstract

Renewable energy sources are explored in order to replace the environmental harmful and depleting fossil fuel source. Sustainable second-generation based bioethanol is ought to be achieved by the biochemical use of microorganisms and enzymes. Nevertheless, no organisms have been discovered in nature that can convert both pentose and hexose sugars, present in the lignocellulosic biomass, at high rate and with high ethanol production yield. The current industrial relevance of Saccharomyces cerevisiae as hexose-fermenting agent makes it an appealing subject for bioengineering towards xylose fermentation and eventual co-consumption. Several strategies are engaged in this matter such as improvement of the endogenous enzymes and pathways, and the integration of the oxidoreductase or isomerase pathway. However, many issues exist in these endeavours. This report will discuss the complications remaining in the engineering of S. cerevisiae towards the hexose- and pentosefermentation of lignocellulosic biomass.

Item Type: Thesis (Bachelor's Thesis)
Supervisor:
Supervisor nameSupervisor E mail
Driessen, A.J.M.A.J.M.Driessen@rug.nl
Degree programme: Biology
Thesis type: Bachelor's Thesis
Language: English
Date Deposited: 15 Nov 2019
Last Modified: 15 Nov 2019 13:25
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/21215

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