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On the Source of the Ingression Force during Bacterial Cytokinesis

Boersma, Auke (2019) On the Source of the Ingression Force during Bacterial Cytokinesis. Master's Thesis / Essay, Biomolecular Sciences.

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Abstract

In order for bacteria to replicate, they need to fully constrict their membrane(s) and cell wall inwards, forming two separate cells. How the ingression force required for membrane constriction is generated, has been debated for several decades. The two most likely candidates for force generation are FtsZ and peptidoglycan synthesis. FtsZ has long been the most promising of the two, showing a capability to constrict vesicles on its own in vitro. However, various studies in recent years have demonstrated that PG synthesis is in fact the more probable force generator, able to perform cell division independent of FtsZ. This essay will explain the history behind both models and discuss their validity.

Item Type: Thesis (Master's Thesis / Essay)
Supervisor name: Scheffers, D.J.
Degree programme: Biomolecular Sciences
Thesis type: Master's Thesis / Essay
Language: English
Date Deposited: 14 Jan 2020 10:14
Last Modified: 14 Jan 2020 10:14
URI: https://fse.studenttheses.ub.rug.nl/id/eprint/21372

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