Huang, Armando (2020) Potential therapeutics and vaccine candidates for coronavirus disease-2019. Bachelor's Thesis, Pharmacy.
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Abstract
The novel coronavirus, a single-stranded positive-sense RNA, emerged from Wuhan has caused a global pandemic, causing surge of COVID-19 patients in hospital systems worldwide. Previous zoonotic coronaviruses outbreaks provided us knowledge on the immunopathology and the function of viral components, paving the way for the COVID-19 therapeutics and vaccine development. This article provides insight into pharmaceutical interventions, identifying potential COVID-19 therapeutics and vaccines. As of May 23rd, 2020, there were 223 therapeutics and 141 vaccines in clinical trials. Some of the COVID-19 therapeutics and vaccines showed promising preliminary results and other negative results. However, it is difficult to determine whether they have an essential role in COVID-19 treatment in the future since most of the trials have their shortcomings. Remdesivir is the only drug approved for COVID-19. Lesson learned from this pandemic is that new clinical trial design needs to be designed to speed up therapeutic development for future pandemic.
| Item Type: | Thesis (Bachelor's Thesis) |
|---|---|
| Supervisor name: | Groves, M.R. |
| Degree programme: | Pharmacy |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 04 Jun 2020 11:18 |
| Last Modified: | 04 Jun 2020 11:18 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/22007 |
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