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Bispecific Antibody-Drug Conjugates

Tsousi, Vasiliki (2020) Bispecific Antibody-Drug Conjugates. Master's Thesis / Essay, Biomolecular Sciences.

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Abstract

Bispecific antibodies have gain great interest the last decades and relevant studies have come up with new possibilities in their therapeutic applications. A special interest is acquired in the design of bispecific antibody drug conjugates, that allows targeted delivery of therapeutic payloads in the body, with great specificity and efficacy. Many technologies have been developed for the successful design of bispecific ADC, focusing on the production of different bispecific ADC formats, the optimization of their efficacy, their linkage with the drug and the way of their administration. This essay will review these aspects as well as the technologies designed on them and it will present relevant studies.

Item Type: Thesis (Master's Thesis / Essay)
Supervisor name: Bogaart, G. van den and Bianchi, F.
Degree programme: Biomolecular Sciences
Thesis type: Master's Thesis / Essay
Language: English
Date Deposited: 10 Jul 2020 11:04
Last Modified: 10 Jul 2020 11:04
URI: https://fse.studenttheses.ub.rug.nl/id/eprint/22573

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