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Mucosal immunity: the thin line between hypo- and hyperresponse to gut associated bacteria

Rohde, J.H. (2010) Mucosal immunity: the thin line between hypo- and hyperresponse to gut associated bacteria. Bachelor's Thesis, Biology.

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Abstract

The intestinal immune system and its interaction with resident and pathogenic bacteria has been a field of intense research in the past years. The purpose of this thesis is to give an overview of the different parts of the intestinal mucosal immunity and to discuss how they interact with microbes to confer protection against pathogenic species as well as preventing unnecessary reactions to commensal bacteria. Inflammatory bowel disease and irritable bowel syndrome as examples of overreaction to intestinal microbes will also be discussed as well as induction and prevention of autoimmunity and allergy through intestinal bacteria. The last part will discuss Shigella, a pathogen which makes its home in the intestine of the host and how it can escape the immune defenses and even use them for its advantage. Since many questions still remain to be answered in this field of research, this thesis can only give an overview of the current hypothesis and models of immune action.

Item Type: Thesis (Bachelor's Thesis)
Degree programme: Biology
Thesis type: Bachelor's Thesis
Language: English
Date Deposited: 15 Feb 2018 07:31
Last Modified: 15 Feb 2018 07:31
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/9245

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