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Fragmentation of leucine-enkephalin by collision induced dissociation for different keV projectile ions

Door, M. (2010) Fragmentation of leucine-enkephalin by collision induced dissociation for different keV projectile ions. Bachelor's Thesis, Chemistry.

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Abstract

It is still unexplored how keV ions interact with isolated DNA molecules and into which fragments the DNA eventually dissociates. Such knowledge is important for the improvement of proton (tumor) therapy since DNA damage is one of the basic mechanism underlying biological radiation damage. Experiments on ion induced dissociation are performed with the new Paultje setup at the Kernfysisch Versneller Instituut (KVI) of the Rijksuniversiteit of Groningen. This bachelor thesis describes the experimental setup and performed experiments which are subsequently analyzed. In our experiments Leucine-enkephalin, a penta- eptide also found in humans, is irradiated with Heq+ ions of different charge state and velocity.

Item Type: Thesis (Bachelor's Thesis)
Degree programme: Chemistry
Thesis type: Bachelor's Thesis
Language: English
Date Deposited: 15 Feb 2018 07:45
Last Modified: 15 Feb 2018 07:45
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/9446

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