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A review of the multi-functional protein YidC that is involved in the insertion and folding of membrane proteins

Oldebesten, A.O.G. (2011) A review of the multi-functional protein YidC that is involved in the insertion and folding of membrane proteins. Bachelor's Thesis, Biology.

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Abstract

YidC is a multi-functional protein that belongs to the Oxa family of membrane proteins. In this review the different functions, such as the insertase and the chaperone function, of YidC are reviewed. YidC has several homologs found in different membranes such as the thylakoid membrane in the chloroplast, the inner membrane of mitochondria and the bacterial inner membrane. All of these homologs have functions that are involved in the insertion or assembly of energy generation complexes. YidC is able to insert proteins in collaboration with the Sec-translocase and through a YidC only pathway. Another function of YidC is a chaperone function that is involved in the folding of membrane proteins. The role of YidC in the insertion of the MscL protein is disputed. This review takes a closer look on the role of YidC in MscL membrane insertion.

Item Type: Thesis (Bachelor's Thesis)
Degree programme: Biology
Thesis type: Bachelor's Thesis
Language: English
Date Deposited: 15 Feb 2018 07:45
Last Modified: 15 Feb 2018 07:45
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/9601

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