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The Aging Brain

Lentferink, D.H. (2011) The Aging Brain. Bachelor's Thesis, Biology.

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Abstract

Because life expectancy has risen, aging is becoming a hot topic. Especially the aging brain has gained in interest since the effects of cognitive decline are becoming a great burden to our health care and costs the government a great deal of money. Cognitive decline is due to neuronal cell death, synaptic dysfunction, decreased neuroendocrine function, loss of calcium homeostasis and the failure of stem cells compensating for the age related loss of cells. There is nothing that can be done to treat or even prevent cognitive decline, so more research is needed in this area. Transgenic studies in knock-out mice could maybe help us understand the healthy aging process in humans. A list of genes associated with accelerated aging in mice and a list of genes associated with extended lifespan in mice has been included as an addendum to this review. The lack of studies using an integrated approach on aging could explain why we don’t fully understand aging yet.

Item Type: Thesis (Bachelor's Thesis)
Degree programme: Biology
Thesis type: Bachelor's Thesis
Language: English
Date Deposited: 15 Feb 2018 07:45
Last Modified: 15 Feb 2018 07:45
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/9625

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