Doddema, F (2013) Missing value estimation for DNA microarrays. Bachelor's Thesis, Mathematics.
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Abstract
A DNA microarray is a biological tool to measure the activity of genes in different samples. These samples are, for example, coming from a tumor. A DNA microarray can measure simultaneously the activity for M genes in N samples, where M is approximately 20.000 and N is approximately 20. The results can be given as an MxN matrix, the expression matrix E. Sometimes elements in this matrix are missing due to various factors, for example dust on the chip or machine error. In this thesis we describe several methods to estimate the missing values. We compare these methods using some DNA microarray (online available).
| Item Type: | Thesis (Bachelor's Thesis) |
|---|---|
| Degree programme: | Mathematics |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 15 Feb 2018 07:53 |
| Last Modified: | 15 Feb 2018 07:53 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/11018 |
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