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The organization of the actin homologue MreB in bacteria

Rheenen, M.D. van (2014) The organization of the actin homologue MreB in bacteria. Master's Thesis / Essay, Biology.

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A major research topic in cell shape research is the function of the protein MreB. Over the last 15 years several research groups have presented evidence, mostly based on fluorescence microscopy techniques, both in favour of and against a model that describes MreB as a helical structure, possibly spanning from pole to pole in rod-shaped bacteria, mostly Escherichia coli and Bacillus subtilis. Different properties of MreB have been studied such as length of filaments and speed of movement, as well as its response to nutrient and oxygen depletion. In this paper a selection of articles on this subject, published in highly regarded scientific journals, is reviewed and the different results and arguments are discussed. Based on the reviewed material I feel that filaments of a certain length, that extend a good part of a turn around the cell periphery and aligning relatively parallel to each other along the length of the cell are the likely candidates for MreB organization in healthy cells.

Item Type: Thesis (Master's Thesis / Essay)
Degree programme: Biology
Thesis type: Master's Thesis / Essay
Language: English
Date Deposited: 15 Feb 2018 07:59
Last Modified: 15 Feb 2018 07:59

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