Groen, J. (2016) CRISPR/Cas9 a Versatile Tool in Bio-Engineering. Bachelor's Thesis, Biology.
|
Text
LST_BC_2016_JGroen.pdf - Published Version Download (1MB) | Preview |
|
![[img]](https://fse.studenttheses.ub.rug.nl/style/images/fileicons/text.png) |
Text
Toestemming.pdf - Other Restricted to Backend only Download (450kB) |
Abstract
Clustered interspaced short palindromic repeats (CRISPR) with CRISPR associated 9 (Cas9) is a new bio-engineering tool originating from bacteria. It is a powerful and versatile tool to target and bind genes of interest using RNA guidance and is subsequently able to edit or regulate genes. Cas9 can be used as a machinery that induces double-stranded breaks or it can be used to regulate genes in various ways. This review covers various aspects such as basic mechanisms of CRISPR/Cas9, CRISPR/Cas9 experimental design, off-target effects caused by CRISPR/Cas9, and catalytically inactive Cas9 with its versatile functions.
| Item Type: | Thesis (Bachelor's Thesis) |
|---|---|
| Degree programme: | Biology |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 15 Feb 2018 08:11 |
| Last Modified: | 15 Feb 2018 08:11 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/13720 |
Actions (login required)
 |
View Item |