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Blood flow velocity changes in the brain due to the loss of water after exercising

Dekker, T. (2016) Blood flow velocity changes in the brain due to the loss of water after exercising. Research Project 1 (minor thesis), Biomedical Sciences.

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Irrespective of changes in blood pressure, as a result of exercise, the cerebral blood flow remains constant due to cerebral autoregulation. During exercise the body loses water by sweating, which may affect the cerebral blood flow velocity. Transcranial Doppler can measure the cerebral blood flow velocity in, among others, the middle cerebral artery. We hypothesize that after endurance exercising the loss of water causes the middle cerebral artery blood flow velocity profile to change and to decrease on average. Seventeen healthy individuals cycled for 90 minutes twice at a one week interval. The first time they were not allowed to drink water and the second time they drank water after 45 minutes of exercise. Before and after exercise blood flow velocity was measured with Transcranial Doppler. Participants lost on average 1,17 ± 0,39 kg of water after exercise during the first visit. Exercise and loss of water did not change the middle cerebral artery flow velocity. However, adding water to the body by means of drinking water or passive leg raising in combination with exercise caused several middle cerebral artery flow velocity parameters to change. In conclusion, cerebral autoregulation keeps the blood flow velocity stable after exercise and loss of water. The adaptations made as a response to the loss of water due to exercise probably stays active when adding water, which causes changes in the middle cerebral artery flow velocity profile.

Item Type: Thesis (Research Project 1 (minor thesis))
Degree programme: Biomedical Sciences
Thesis type: Research Project 1 (minor thesis)
Language: English
Date Deposited: 15 Feb 2018 08:13
Last Modified: 15 Feb 2018 08:13

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