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Membraneless organelles and how to simulate their molecular structure

Chaillet, Marten (2019) Membraneless organelles and how to simulate their molecular structure. Master's Thesis / Essay, Molecular Biology and Biotechnology (2016-2019).


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Membraneless organelles form through phase separation. Such a process can be driven by complex coacervation. Two polymers of opposite charge interact to form a separate phase in solution. This essay describes this in the context of biological phase separation. Interactions of proteins involved in droplet assembly are more complex. To understand the full set of interactions new approaches are required. One such approach might be found in molecular dynamics simulations.

Item Type: Thesis (Master's Thesis / Essay)
Supervisor name: Marrink, S.J. and Frederix, P.W.J.M.
Degree programme: Molecular Biology and Biotechnology (2016-2019)
Thesis type: Master's Thesis / Essay
Language: English
Date Deposited: 20 Feb 2019
Last Modified: 04 Mar 2019 10:30

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