Techno-economic analysis of a pharmaceutical grade magnesium stearate production process

Jonker, Niek (2019) Techno-economic analysis of a pharmaceutical grade magnesium stearate production process. Integration Project, Industrial Engineering and Management.

Preview	Text Bachelor_IEM_2019_N.F.Jonker.pdf Download (850kB) | Preview
	Text toestemming.pdf Restricted to Registered users only Download (118kB)

Abstract

For many years the local economy of Oost-Groningen has been declining. An initiative called Innovatie Hub Oost Groningen has identified this problem and wants to solve it by encouraging more economic activity of the companies in the region. Two of these companies are Nedmag and Ten Kate which respectively produce magnesium hydroxide and lard stearin. These two products can be processed to a high value product; pharmaceutical grade magnesium stearate. This magnesium stearate is used in the pharmaceutical industry as a lubricant in tablet production. This research is focused on the production process of this pharmaceutical grade magnesium stearate from magnesium hydroxide of Nedmag and lard stearin from Ten Kate. First the product requirements of the pharmaceutical industry set to magnesium stearate are discussed. Then the magnesium hydroxide from Nedmag and lard stearin from Ten Kate are analyzed on their chemical composition. After which, the production process of obtaining stearic acid from the lard stearin of Ten Kate is given. Next, the production process of obtaining pharmaceutical grade magnesium stearate from stearic acid and magnesium hydroxide is stated. Lastly, the capital cost of the magnesium stearate production processes is estimated.

Item Type:	Thesis (Integration Project)
Supervisor name:	Heeres, H.J.
Degree programme:	Industrial Engineering and Management
Thesis type:	Integration Project
Language:	English
Date Deposited:	26 Jun 2019
Last Modified:	27 Jun 2019 07:44
URI:	https://fse.studenttheses.ub.rug.nl/id/eprint/19719

Actions (login required)

View Item