Vermeulen, JM (2020) An overview: functionality of the prefrontal cortex. Bachelor's Thesis, Biology.
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Abstract
The prefrontal cortex is a complex and substantial part of the brain. It mediates the control of multiple high-level cognitive behaviours. To better understand the functionality of this part of the brain, in this review, convergent research will be discussed to answer the question how the prefrontal cortex is involved in cognitive processes like decision making, the forming of memory, and the behavioural expressions associated with stress. To do so, an analysis of the neurophysiological components and contents of the prefrontal cortex is made. These components will be explored in the rodent model of stress and memory and will be examined with optogenetic tools. Results based on the functionality of the neurophysiology show a great involvement and connectivity of the subsets of the prefrontal cortex in processes as learning, decision making and the processing of sensory information and giving this information a value for projections to other areas of the brain. The newly developed tool of optogenetics showed that subsets of the behavioural output concerning the phenomena like stress and memory can be altered and sometimes even induced as a result of this optogenetic manipulation. The optogenetic tool and rodent model prove themselves important for future understanding and examining the functionality of the prefrontal cortex.
| Item Type: | Thesis (Bachelor's Thesis) |
|---|---|
| Supervisor name: | Buwalda, B. |
| Degree programme: | Biology |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 04 May 2020 12:03 |
| Last Modified: | 04 May 2020 12:03 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/21839 |
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