van de Poll, Jeroen, B (2020) Future Prospects of the Applications of CRISPR/Cas9 in Cancer Research and Therapy. Bachelor's Thesis, Life Science and Technology.
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Abstract
CRISPR/Cas9 is a possibly revolutionizing strategy for cancer research and therapy. Through (epi)genomic editing CRISPR technology can insert and delete DNA segments, allowing for interactions with oncogenes and tumour-suppressor genes. In this thesis, I will investigate my research question: What will the recent developments concerning the CRISPR/Cas9 complex effectuate in cancer research and therapy? Currently, research is being conducted worldwide to clarify the function, potential and drawbacks of CRISPR/Cas9. Multiple pathways are used to introduce various strategies concerning CRISPR therapy and research. Specifically, multiple strategies for cancer therapy and research are being developed through CRISPR/Cas9 such as cancer immunotherapy through CRISPR/Cas9 and oncolytic viruses. Though, there are potential pitfalls and risks. This thesis specifically studies the possibilities of CRISPR/Cas9 in the search for innovation in research and new therapies in cancer, and what previous developments would effectuate for the cancer field. CRISPR provides life sciences with a highly demanded tool which exceeds current gene-editing technology. Even though, details of the potential pitfalls and risks of CRISPR/Cas9 need to be addressed to further gain benefit from this technology. CRISPR/Cas9 is one of the highest impact discoveries of our time and has the capabilities to contribute to a promising future of mankind and could allow our species to flourish through times.
| Item Type: | Thesis (Bachelor's Thesis) |
|---|---|
| Supervisor name: | Kruyt, F.A.E. and Foijer, F. |
| Degree programme: | Life Science and Technology |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 24 Jun 2020 12:42 |
| Last Modified: | 24 Jun 2020 12:42 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/22124 |
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