Bijlsma, Ewout (2020) Designing antimicrobial peptides. Bachelor's Thesis, Life Science and Technology.
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Abstract
Antibiotic resistance is on the rise, with more and more multiple-antibiotic resistant bacteria being found. The classic way of semi synthetic antibiotics has long since yielded a completely new result, so we must find another way. Eukaryote derived and microbe modified antimicrobial peptides are nature’s way to, especially in marine organisms, fight off pathogenic bacteria and remain a healthy host. Some of these are modified to an extent not that is rarely seen in the world, with up to 30 modified amino acids in a peptide only 48 amino acids long. How can we use these types of peptides to further research into novel antimicrobial peptides? Here we find that antimicrobial peptides usually have a length of 30-40 amino acids and a charge of +3 to +4, along with all different kinds of modifications, even some only very recently described for the first time, which may help design anti-microbial peptides.
Item Type: | Thesis (Bachelor's Thesis) |
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Supervisor name: | Kuipers, O.P. |
Degree programme: | Life Science and Technology |
Thesis type: | Bachelor's Thesis |
Language: | English |
Date Deposited: | 30 Jun 2020 09:54 |
Last Modified: | 30 Jun 2020 09:54 |
URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/22251 |
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