Raharjanto, Ariq (2020) Comparative Analysis of Bio-based Azelaic Acid Synthesis Methods and Techno-Economic Evaluation of Theoretical Process Design. Bachelor's Thesis, Chemical Engineering.
|
Text
bCEng_2020_RaharjantoA.pdf Download (775kB) | Preview |
|
![[img]](https://fse.studenttheses.ub.rug.nl/style/images/fileicons/text.png) |
Text
toestemming.pdf Restricted to Registered users only Download (95kB) |
Abstract
Azelaic acid has been commercially produced for over 50 years for its uses as a plasticizer, lubricant, skincare treatment etc. It is currently industrially produced by oxidizing oleic acid with ozone to obtain the dicarboxylic acid, azelaic acid, and monocarboxylic acid, pelargonic acid. Over the past few years, alternative methods for synthesis of azelaic acid have been developed to overcome the large energy demands and form a greener process by using different chemicals and techniques. These methods were explored in this report and ranked according to appropriate Principles of Green Chemistry to determine an ideal method for designing a process for commercial production. Methods researched included both methods already used in industry and more novel approaches. The general approaches involved ozo-nolysis of oleic acid, catalytic oxidation and chemo-enzymatic approaches. The main factors that came into consideration were the safety and sustainability of the solvents used in each reaction, the human and environmental impacts of the reagents, use of catalysts and the highest yields of azelaic acid re-ported. It was found that a catalytic oxidation method described by V. Benessere [21], and further op-timized by Z. Masyithah [23], that utilized H2O2 and H2WO4 catalyst to oxidize oleic acid without the use of solvents to obtain a yield of 91% for azelaic acid was the most ideal in terms of its overall “green” and production value.
| Item Type: | Thesis (Bachelor's Thesis) |
|---|---|
| Supervisor name: | Heeres, H.J. and Deuss, P.J. and Lahive, C.W. |
| Degree programme: | Chemical Engineering |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 10 Jul 2020 11:12 |
| Last Modified: | 10 Jul 2020 11:12 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/22508 |
Actions (login required)
 |
View Item |