Raghunath, Chandan (2020) The role of gut microbiome in health and disease. Master's Thesis / Essay, Biomolecular Sciences.
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Abstract
A new era of understanding the working mechanism of the human body with respect to health and disease has brought about a lot of insights towards trillions of prokaryotic and eukaryotic organisms constituting the gut microbiome and is being explored in order to better understand how the human body develops these gut microbiota and what their role is in maintaining homeostasis in the body. Maintaining a healthy gut microbiome is the key to tackling many diseases such as inflammatory bowel disorder, obesity, diabetes, asthma and even colorectal cancer. A fascinating connection between the gut and the brain known as the gut-brain axis is being studied and explains how mental health and behaviour is related to the gut microbiome and also helps recognise the interplay between the gut health and neurological disorders such as autism, Parkinson’s disease and multiple sclerosis. Although there are a lot of factors (such as mode of delivery during birth, the living environment and exposure to allergens) determining the composition of the gut microbiome in an individual, the major factor is the type of diet that is followed. A high fiber diet is broken down in the gut by several types of bacterial species that releases metabolites such as short chain fatty acids (SCFAs) which plays a huge role in maintaining a healthy balance in the gut and in turn the whole body. The importance of gut microbiome is increasing and may be the key to a futuristic way to treat any disease.
| Item Type: | Thesis (Master's Thesis / Essay) |
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| Supervisor name: | Euverink, G.J.W. |
| Degree programme: | Biomolecular Sciences |
| Thesis type: | Master's Thesis / Essay |
| Language: | English |
| Date Deposited: | 10 Jul 2020 09:56 |
| Last Modified: | 10 Jul 2020 09:56 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/22568 |
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