Alberts, Julia, J.M.K. (2021) The assessment of the dynamics of cAMP hydrolysis. Research Project, Pharmacy.
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Abstract
The aim of this project is to elucidate whether there are global changes in cAMP levels in the presence of mutant PDE3A and whether this causes changes in kinase activity. In this project, an attempt to purifying the PDE3A1 isoform next to the already successfully purified PDE3A2 will be made. The mainly heart located PDE3A1 isoform could potentially show different hydrolysing properties as the PDE3A2 isoform found in the vascular smooth muscle cells, which is of interest for elucidating more about the mechanism of HTNB.
| Item Type: | Thesis (Research Project) |
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| Supervisor name: | Schmidt, M. |
| Degree programme: | Pharmacy |
| Thesis type: | Research Project |
| Language: | English |
| Date Deposited: | 17 Mar 2021 11:05 |
| Last Modified: | 17 Mar 2021 11:05 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/24086 |
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