Feenstra, Wietske (2021) The truth behind irisin: A descriptive review on the physiology of an exercise-inducible wonder hormone. Bachelor's Thesis, Life Science and Technology.
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Abstract
Irisin is a recently discovered so-called wonder hormone that has gained a great deal of attention over the past decade. It has been proposed as the answer to weight loss on social media due to its fat burning properties. The existence of irisin was, however, not immediately accepted and several recent studies still yield rather contradictory results. As an exercise-inducible adipomyokine, irisin is thought to confer a great deal of the health benefits previously attributed to physical activity. While it was first proposed as a novel therapeutic target in metabolic disorders, many researchers now claim its therapeutic potential in numerous additional pathologies. Much less, however, is known about the physiological role of irisin in a healthy state. The current study aims to provide insight into the physiology of irisin as well as its therapeutic promise. As irisin is produced by a variety of tissues, mainly skeletal muscle, and affects an extensive range of bodily systems, it is presumably involved in more than one physiological mechanism. Diverse factors influence circulating irisin levels and there is abundant controversy on which biochemical and/or environmental influences may truly play a role in its regulation. Based on current knowledge regarding the physiology of irisin, the present study hypothesizes that this newly identified hormone fulfils a role in exercise physiology, aiding in whole-body adaptation to physical activity and preventing exercise-induced...
| Item Type: | Thesis (Bachelor's Thesis) |
|---|---|
| Supervisor name: | Scheurink, A.J.W. |
| Degree programme: | Life Science and Technology |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 26 Jul 2021 09:23 |
| Last Modified: | 26 Jul 2021 09:23 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/25389 |
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