Jansen, Robert (2021) A Better Understanding of Seasonal Influenza Virus A Evolution to Increase Efficacy of Vaccination for Epidemic Prevention. Bachelor's Thesis, Life Science and Technology.
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Abstract
Despite many improvements in surveillance and pharmaceutical development during the past decades, seasonal influenza virus epidemics are not yet under control. The evolutionary characteristics of influenza virus enables escape from immune responses, resulting in yearly epidemics. A better understanding of the antigenic evolution, molecular mechanisms and vaccination strategies have been sought to increase vaccination efficacy and prevention levels against these epidemics. Vaccination against seasonal influenza has become common in most countries globally, but the extent and specific vaccination strategies are not up to date with the knowledge we have today. This thesis explains the mechanisms of the epidemiology of the influenza virus, combined with the molecular knowledge acquired over the past decades and links it to vaccination strategies. Opportunities for better protection and prevention are within our grasp, but it is of importance to put this knowledge into practice and create a better suited strategy to prevent epidemics and pandemics, that populations have been dealing with the past centuries.
| Item Type: | Thesis (Bachelor's Thesis) |
|---|---|
| Supervisor name: | Vos, M.G.J. de |
| Degree programme: | Life Science and Technology |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 13 Oct 2022 12:40 |
| Last Modified: | 13 Oct 2022 12:40 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/25444 |
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