Wind, Sanne (2021) To be or not to be: The heterologous prime-boost vaccination against SARS-CoV-2. Master's Thesis / Essay, Biomedical Sciences.
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Abstract
This paper discusses the current knowledge of SARS-CoV-2, the immune response upon infection, the concept of heterologous prime-boost approaches, and how the latter may be applied in vaccination programs against SARS-CoV-2. A broad summary of SARS-CoV-2 is followed up by a detailed description of the immune response and pathophysiology upon infection. The advantages and disadvantages of the current used vaccines are described. Thereafter, the concept of heterologous prime-boost regimes is introduced, which is followed up by a review of the immunogenicity and safety of combining mRNA vacccines and adeno vector vaccines.
| Item Type: | Thesis (Master's Thesis / Essay) |
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| Supervisor name: | Helfrich, W. |
| Degree programme: | Biomedical Sciences |
| Thesis type: | Master's Thesis / Essay |
| Language: | English |
| Date Deposited: | 30 Jul 2021 09:56 |
| Last Modified: | 30 Jul 2021 09:56 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/25524 |
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