Algra, Bindert, O. (2021) A molecular approach towards treating SARS-CoV-2. Bachelor's Thesis, Biology.
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Abstract
Currently against SARS-CoV-2 only vaccines and broad spectrum antiviral drugs exist. Vaccines can become less effective due to mutations of the virus, referred to as variants of concern. Current drugs are not specifically developed for SARS-CoV-2, and do not counteract all the antagonising effects the virus causes. To develop new medications for treatment of the virus, the replication cycle of SARS-CoV-2 needs to be understood on a molecular level. The nucleocapsid protein of SARS-CoV-2, responsible for packaging the viral genome, plays a large role in the replication cycle as well through a process called liquid-liquid phase separation. Understanding this process and being able to disrupt it is an attractive target for the development of new drugs. Because the nucleocapsid functionality is essential for SARS-CoV-2 infectivity.
| Item Type: | Thesis (Bachelor's Thesis) |
|---|---|
| Supervisor name: | Linskens, M.H.K. |
| Degree programme: | Biology |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 31 Aug 2021 14:01 |
| Last Modified: | 31 Aug 2021 14:01 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/25898 |
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