Jong, Esmee, de (2021) The influence of social housing on behaviour and brain plasticity in rodents. Master's Thesis / Essay, Biomedical Sciences.
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Abstract
Social isolation, loneliness and their effects on health and the brain are more applicable than ever because of the global pandemic caused by COVID-19. Billions of people are quarantined in their own homes as different governments have announced a lockdown causing many people to be socially isolated. Social isolation in rodent models can have negative effects on both the brain and rodent behaviour. Examples of changes in the brain are alterations in the hippocampal CA1 region and the glutamate-GABA cycle. Changes in behaviour may cause an increase in the risk on diseases such as Schizophrenia, depression/anxiety disorders, seizures and epilepsy. On the contrary, environmental enrichment can have positive effects on behaviour, hippocampal CA1 neurons and the glutamateGABA cycle by counteracting for the damage done by social isolation. Environmental enrichment could also help in the treatment or possibly prevention of autism spectrum disorders, Alzheimer’s disease and seizures. This indicates the importance of social/environmental enrichment and the risks that can be induced by the social isolation during this time of the COVID-19 pandemic.
| Item Type: | Thesis (Master's Thesis / Essay) |
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| Supervisor name: | Havekes, R. |
| Degree programme: | Biomedical Sciences |
| Thesis type: | Master's Thesis / Essay |
| Language: | English |
| Date Deposited: | 10 Feb 2022 11:30 |
| Last Modified: | 10 Feb 2022 11:32 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/26581 |
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