Drug related problems in patients treated with oral oncolytic drugs and their association with medication adherence and drug spillage.

Blijham, Margriet (2022) Drug related problems in patients treated with oral oncolytic drugs and their association with medication adherence and drug spillage. Master's Research Project 1, Medical Pharmaceutical Sciences.

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Abstract

Introduction. With three cancer types in the top ten causes of death in the Netherlands, cancer is a major problem in society (Centraal Bureau voor de Statistiek, 2021). Therapy is shifting from surgical procedures, chemotherapy and/or radiation toward targeted oral therapy at home (Schott et al., 2011). This study aims primarily to identify drug related problems (DRPs) and adherence of patients treated with oral oncolytic drugs and secondarily to find out how often these drugs are wasted and what the main causes therefore are. Method. Thirty patients were questioned about their DRPs, adherence and medication waste during up to four interview sessions in three months. The outcomes of the interviews are analysed via an CRF. The results are analysed using descriptive statistics in IBM Statistics SPSS 23.0 and simple calculation in Excel 365 version 2205. Results. Patients reported mainly problems with toxicity, unconscious non-adherence, and practical subjects. The overall adherence of the patients was high. The most often mentioned lack in adherence is the intake on a different time than prescribed. The waste of medication during the research is estimated on €11,935.37, which is €2,935.76 per patient per year. The major reason for medication waste is change of medication. Discussion. Adherence in patients is high and can be given a boost with extra help from HCWs. Patients mainly suffer from adverse effects, which can be supported by HCWs. The wasted medication is still a pro

Item Type:	Thesis (Master's Research Project 1)
Supervisor name:	Boven, J.F.M. van and Bemt, P.M.L.A. van den
Degree programme:	Medical Pharmaceutical Sciences
Thesis type:	Master's Research Project 1
Language:	English
Date Deposited:	13 Jun 2022 09:57
Last Modified:	13 Jun 2022 09:57
URI:	https://fse.studenttheses.ub.rug.nl/id/eprint/27279

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