Achterberg, Tristan (2022) Reviewing the Mechanisms and Causal Relationship Between Periodontitis and Cardiovascular Disease. Bachelor's Thesis, Biology.
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Abstract
As cardiovascular diseases continue to prevail as the leading cause of death worldwide, identifying risk factors that increase risk of CVD is more necessary than ever. Periodontitis has been suggested as a risk factor contributing to the development of CVD in the early 20th century; however, the evidence behind it remains controversial to this day and no clear consensus has been reached. In this review, I focus on the most plausible and well researched mechanisms that have been suggested to play part in bringing about CVD as a consequence of periodontitis. Seemingly, there is convincing evidence behind all the mechanisms discussed, although, none have been undoubtably proven. The evidence does suggest a causal relationship between the two, with periodontal treatment improving CVD-related risk factors; however, the evidence remains insufficient. The reason for this could lie in the fact that cohorts of this nature bring about ethical implications and sample sizes haven’t yet been sufficient to draw definitive conclusions. The studies discussed in this review suggest both a causal and a non-causal relationship and I highlight their most prominent features as well as identify their shortcomings. I present a nonbiased overview of the available evidence, and equally give emphasis on both the evidence suggesting a link between CVD and periodontitis as well as the evidence claiming no link between the two.
| Item Type: | Thesis (Bachelor's Thesis) |
|---|---|
| Supervisor name: | Bogaart, G. van den |
| Degree programme: | Biology |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 21 Jul 2022 09:59 |
| Last Modified: | 21 Jul 2022 09:59 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/28085 |
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