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The potential role of bacteria associated with the development of ulcerative colitis and Crohn’s disease’s etiology.

Kepekepe, Sibongile Chevaun (2022) The potential role of bacteria associated with the development of ulcerative colitis and Crohn’s disease’s etiology. Bachelor's Thesis, Life Science and Technology.

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Abstract

Our microbiota is the result of millions of years of co-evolution and adaptation. The human microbiota is the composition of multiple microorganisms and consists of the 10 to 100 trillion symbiotic microbial cells possessed by each person, primarily bacteria in the gut. The relation between human health and the gut microbiota is being progressively recognised. It contributes largely to our health and to diseases, especially diseases that occur in the gastrointestinal tract. Due to this, having knowledge of which particular bacteria and microorganisms in the microbiota contribute to certain diseases is cardinal in order to identify and solve complications which can be life-threatening. Developments in genome sequencing technologies and bioinformatics have now enabled researchers to study these microorganisms and their function and microbe-host interactions in an elaborate manner both in health and diseases . Inflammatory bowel diseases (IBD) are chronic disabling gastrointestinal disorders that harshly impact almost every aspect of an affected individual's life. In Europe, there is an estimated number of 2.5 - 3 million people newly affected by IBD each year. The incidence and prevalence of IBD is increasing (20.2 per 100,000 person-years). Therefore, the aim of this paper is to identify species of bacteria that are associated with the development of IBD and to decipher if there is a similar correlation with these specific bacteria in other diseases

Item Type: Thesis (Bachelor's Thesis)
Supervisor name: Harmsen, H.J.M. and Buist, G.
Degree programme: Life Science and Technology
Thesis type: Bachelor's Thesis
Language: English
Date Deposited: 26 Aug 2022 13:41
Last Modified: 26 Aug 2022 13:41
URI: https://fse.studenttheses.ub.rug.nl/id/eprint/28494

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