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NOISE-INDUCED MILD HEARING LOSS AND COGNITION IN YOUNG MALE WISTAR RATS

Bunn, Fanny (2023) NOISE-INDUCED MILD HEARING LOSS AND COGNITION IN YOUNG MALE WISTAR RATS. Research Project 1 (minor thesis), Behavioural and Cognitive Neurosciences.

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Abstract

The pervasive use of listening devices has raised growing concerns about developmental and educational difficulties following noise-induced hearing loss in children and adolescents. Recent human and rodent studies have suggested a link between noise-induced mild hearing loss and cognitive impediments in young adults that reach well beyond auditory and verbal working memory processes. To date, the exact cognitive consequences following mild hearing loss caused by noise exposure in young adults remain elusive. Therefore, the current study investigated the effects of mild hearing loss induced by noise exposure on spatial, recognition, and social recognition memory in young male Wistar rats. Results showed no significant differences in memory performances between rats with noise-induced mild hearing loss and controls. The study’s findings, however, are limited by further analysis showing that behavioral observations partially failed to exploit rodents' tendency for novelty over-familiarity. These results imply that rats did either not remember the task or the task failed to measure memory performances due to methodological drawbacks. Overall, findings suggest no significant impact of noise-induced mild hearing loss on spatial, recognition and social recognition memory. However, follow-up studies should refine the methodological limitations of the current study and assess the replicability of its findings.

Item Type: Thesis (Research Project 1 (minor thesis))
Supervisor name: Olivier, J.D.A. and Jagersma, J.D.
Degree programme: Behavioural and Cognitive Neurosciences
Thesis type: Research Project 1 (minor thesis)
Language: English
Date Deposited: 08 Jun 2023 10:13
Last Modified: 08 Jun 2023 10:13
URI: https://fse.studenttheses.ub.rug.nl/id/eprint/29987

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