Romkes, Martha (2023) Transdiagnostic Perspectives on ASD and ADHD. Bachelor's Thesis, Life Science and Technology.
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Abstract
This thesis aims to examine the concept of a phenotypic continuum that challenges traditional discrete disorder classifications in neuropsychiatric conditions, particularly autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD). Comorbidity between ASD and ADHD is frequently observed in clinical practice, and traits associated with these conditions often overlap. The disorders frequently co-occur within families, suggesting similar underlying genetics and biological mechanisms. By analyzing recent genetic research linking gene variants to an increased chance of developing a disorder, this thesis proposes that shared genetic risk factors contribute to a broader phenotypical spectrum encompassing ASD and ADHD and potentially other conditions such as schizophrenia (SCZ) and major depressive disorder (MDD) as well. By understanding the effects and interactions of these genes, genetic analysis has the potential to advance personalized diagnostics and treatment, promoting a shift towards more individualized approaches and a nuanced understanding of neurodevelopmental disorders.
| Item Type: | Thesis (Bachelor's Thesis) |
|---|---|
| Supervisor name: | Kas, M.J.H. |
| Degree programme: | Life Science and Technology |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 17 Jul 2023 12:35 |
| Last Modified: | 17 Jul 2023 12:35 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/30727 |
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