Jansen, Alwin (2024) Applications of DNA origami in super-resolution microscopy. Research Paper, Nanoscience.
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Abstract
DNA origami enables the bottom-up fabrication of structures at the nanoscale. Using modified staple strands that guide the structure in place, functional groups can be placed with nm-scale precision onto the so-called origami breadboard. Super-resolution microscopy is a technique in which images are reconstructed from multiple datasets to allow for resolutions below the diffraction limit. Here, we will be looking at three different ways the origami breadboard has been used as a testing ground for super-resolution imaging: DNA-points accumulation in nanoscale topography (DNA-PAINT), FRET-based imaging, and how DNA nanoantennas have been used to place nanoparticles to enhance fluorescent output.
| Item Type: | Thesis (Research Paper) |
|---|---|
| Supervisor name: | Otto, S. |
| Degree programme: | Nanoscience |
| Thesis type: | Research Paper |
| Language: | English |
| Date Deposited: | 14 Jun 2024 13:57 |
| Last Modified: | 14 Jun 2024 13:57 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/32666 |
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