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How the Cerebellum Modulates Activity of the Basal Ganglia During Development and Production of Vocalisation; Insights from Humans and Songbirds

Pijnacker, Robin (2024) How the Cerebellum Modulates Activity of the Basal Ganglia During Development and Production of Vocalisation; Insights from Humans and Songbirds. Master's Thesis / Essay, Behavioural and Cognitive Neurosciences.

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Abstract

Vocal learning is an exceptional sensory-motor skill that is evolutionarily conserved between humans and songbirds. Songbirds serve as valuable models for studying the brain mechanisms underlying vocal learning, which have led to a well-established model of vocalisation in both mammals and birds. This model primarily consists of two components; a motor pathway for generating vocalisations and a feedback loop that ensures the produced sounds match an internal sound template. The motor pathway is associated with the cortex, while the feedback loop involves the basal ganglia and thalamus. This essay introduces the cerebellum as an extra component of the song system. The cerebellum is involved in the coordination and error correction of motor movements and has proven to play a significant role in human speech. Previously, it was believed that the cerebellum and cerebrum had separate functions in movement creation and interacted only at the level of the cortex. However, recent studies have shown that the cerebellum also interacts with the basal ganglia at the thalamic level and has direct projections to regions important for the feedback loop. This essay proposes a new song system model based on insights from both mammals and birds, that integrates the functions of both cerebellum and cerebrum.

Item Type: Thesis (Master's Thesis / Essay)
Supervisor name: Moorman, S.
Degree programme: Behavioural and Cognitive Neurosciences
Thesis type: Master's Thesis / Essay
Language: English
Date Deposited: 30 Jul 2024 12:35
Last Modified: 30 Jul 2024 12:35
URI: https://fse.studenttheses.ub.rug.nl/id/eprint/33695

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