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A Custom Distribution Fitted Random Forest for Accelerated Failure Time Modelling

Duwinanto, Muhammad Rizki (2025) A Custom Distribution Fitted Random Forest for Accelerated Failure Time Modelling. Master's Thesis / Essay, Artificial Intelligence.

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Abstract

Survival Analysis is crucial in healthcare for predicting the occurrence of a specific event in a population, such as a patient’s death or a particular outcome. Most survival analysis methods are currently focused on predicting the survival risk of an event within a certain time, using Random Survival Forest and Neural Networks. To predict the occurrence of time-to-event directly, the Accelerated Failure Time model can be used. Existing methods, such as XGBoost AFT, have already been explored but lack a more data-driven approach. In this research, a random forest is implemented using the Accelerated Failure Time (AFT) loss function to explore the custom-distribution fitting. This research aims to improve the accelerated failure loss function using parametric fitting for three distributions in logarithmic time space of Logistic, Extreme and Normal and non-parametric fitting using Gaussian Mixture Models before the training. Finally, the bootstrapping method is used to avoid overfitting during the distribution fitting process. Custom distribution fitting dramatically enhanced the C-index and metrics, but bootstrapping yielded no better results. The usage of Gaussian mixture models also creates worse training and testing performances. In conclusion, Accelerated Failure Random Forest represents a promising step toward more effective direct time-to-event prediction models.

Item Type: Thesis (Master's Thesis / Essay)
Supervisor name: Schippers, M.B. and Guo, J.
Degree programme: Artificial Intelligence
Thesis type: Master's Thesis / Essay
Language: English
Date Deposited: 12 Sep 2025 08:53
Last Modified: 12 Sep 2025 08:53
URI: https://fse.studenttheses.ub.rug.nl/id/eprint/37028

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