Wolthuis, Gerrit Ype (2026) What the spirometer doesn't tell you: CO2 and the brain in COPD. Master's Thesis / Essay, Biomedical Sciences.
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Abstract
Some patients with severe COPD develop chronic hypercapnia, which is the retention of CO2 due to poor ventilation in the lungs. This disease state is associated with neuroinflammation, a disrupted blood-brain barrier and cognitive impairment. This colloquium investigates cognitive decline in hypercapnic COPD patients, the molecular pathways linking hypercapnia to brain dysfunction and what possible treatments for these patients could be.
| Item Type: | Thesis (Master's Thesis / Essay) |
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| Supervisor name: | Brandsma, C.A. |
| Degree programme: | Biomedical Sciences |
| Thesis type: | Master's Thesis / Essay |
| Language: | English |
| Date Deposited: | 02 Sep 2026 08:06 |
| Last Modified: | 02 Sep 2026 08:06 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/37535 |
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