Eising, S. (2010) Peptide self-replication driven by self-assembly. Bachelor's Thesis, Chemistry.
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Abstract
Self-replication of molecules is probably an essential process in the origin of life. Selfreplicating molecules can be observed with dynamic combinatorial chemistry and already a small numbers of self-replicators are found with this technique. Peptide-derived self-replicating behaviour is achieved with small dynamic combinatorial libraries of a self-binding building block. Fibres are formed from the macrocycles of the building block, because of the stabilisation by the A-sheets between the peptides of the building blocks. To understand better which factors provide the self-assembly and selfreplication of molecules, varying the building block structure is a useful tool. Here the first steps of the synthesis of 2-(2,7-dimercapto-9Hfluoren-9-yl)acetic acid out of fluorene is described.
| Item Type: | Thesis (Bachelor's Thesis) |
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| Degree programme: | Chemistry |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 15 Feb 2018 07:45 |
| Last Modified: | 15 Feb 2018 07:45 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/9459 |
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