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The Transgenerational Transmission of Stress-Induced Traits Through Epigenetic Alterations

van de Haar, Huib Jacob (2018) The Transgenerational Transmission of Stress-Induced Traits Through Epigenetic Alterations. Bachelor's Thesis, Biology.

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Abstract

Lamarckian pathways of inheritance are often grossly overlooked. This paper reviews the transgenerational transmission of traits via stress-induced epigenetic alterations. The prevalence of this transmission is investigated in humans as well as other animals. Stress-induced DNA methylation, histone modifications and non-coding RNAs can all manifest itself into altered phenotypes of subsequent generations. Increased activity of the HPA axis in the offspring of stress-affected individuals is a recurrent finding. Furthermore, potential adaptive capabilities of this transgenerational modification will be discussed, in an attempt to hypothesize the benefits of Lamarckian inheritance.

Item Type: Thesis (Bachelor's Thesis)
Supervisor:
Supervisor nameSupervisor E mail
Beukeboom, L.W.L.W.Beukeboom@rug.nl
Degree programme: Biology
Thesis type: Bachelor's Thesis
Language: English
Date Deposited: 19 Jun 2018
Last Modified: 20 Jun 2018 14:11
URI: http://fse.studenttheses.ub.rug.nl/id/eprint/17381

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