van de Haar, Huib Jacob (2018) The Transgenerational Transmission of Stress-Induced Traits Through Epigenetic Alterations. Bachelor's Thesis, Biology.
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Abstract
Lamarckian pathways of inheritance are often grossly overlooked. This paper reviews the transgenerational transmission of traits via stress-induced epigenetic alterations. The prevalence of this transmission is investigated in humans as well as other animals. Stress-induced DNA methylation, histone modifications and non-coding RNAs can all manifest itself into altered phenotypes of subsequent generations. Increased activity of the HPA axis in the offspring of stress-affected individuals is a recurrent finding. Furthermore, potential adaptive capabilities of this transgenerational modification will be discussed, in an attempt to hypothesize the benefits of Lamarckian inheritance.
Item Type: | Thesis (Bachelor's Thesis) |
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Supervisor name: | Beukeboom, L.W. |
Degree programme: | Biology |
Thesis type: | Bachelor's Thesis |
Language: | English |
Date Deposited: | 19 Jun 2018 |
Last Modified: | 20 Jun 2018 14:11 |
URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/17381 |
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