Gaifas, Lorenzo (2020) Advances in Cryo-ET and Subtomogram Averaging. Master's Thesis / Essay, Biomolecular Sciences.
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Abstract
Cryo Electron Tomography (Cryo-ET) - which stems from the better known Cryo Electron Microscopy - is a powerful imaging technique that allows for high resolution structure determination of single samples in native conformation or in situ. Recent engineering and computational advances brought Cryo-ET back to the front-line of structural biology, opening up new applications and possibilities. Here, we describe the state of the art of Cryo-ET, with a particular focus on subtomogram averaging for single particle studies, and explore the recent technological advances that prove most promising for the future of this technique.
| Item Type: | Thesis (Master's Thesis / Essay) |
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| Supervisor name: | Batista Paulino, C. |
| Degree programme: | Biomolecular Sciences |
| Thesis type: | Master's Thesis / Essay |
| Language: | English |
| Date Deposited: | 25 Aug 2020 08:27 |
| Last Modified: | 25 Aug 2020 08:27 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/23214 |
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